One of the campaigns we test most often on our clients’ ad accounts, just because it is so profitable, is the Super LAL CBO.
It’s basically a CBO Campaign using 5 adsets with the same audience: a stack of your 8 best Lookalikes 1% (the most profitable from your tests).
You want to stack those lookalikes and then duplicate the final audience 5 times because you'll end up with a pretty large audience made of some of your best cold audiences. Duplicating it 5 times means you are going to find some profitable pockets,and once you have, you can just optimise the campaign, switching off everything but the adset that is bring you the sales. And the game is done.
It usually works very well at scale with a daily budget of €300 on this campaign alone, but it’s always worth testing it with smaller budgets too.